Mail Stop 3651 May 10, 2006 Via U.S. Mail and Facsimile Earl E. Congdon Chief Executive Officer Old Dominion Freight Line, Inc. 500 Old Dominion Way Thomasville, NC 27360 RE: Old Dominion Freight Line, Inc. Form 10-K for the Fiscal Year Ended December 31, 2004 Form 10-K for the Fiscal Year Ended December 31, 2005 File No. 000-19582 Dear Mr. Congdon: We have completed our review of your Form 10-K and related filings and do not, at this time, have any further comments. Sincerely, Joe Foti Senior Assistant Chief Accountant Via facsimile: Wes Frye, Senior Vice President - Finance (336) 822-5289 Earl E. Congdon Old Dominion Freight Line, Inc. May 10, 2006 Page 2